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Keyword Search Criteria: Adaptive Design returned 40 record(s)
Sunday, 07/30/2017
An Optimized Adaptive Enrichment Design for Multi-Arm Trials
Michael Rosenblum, Johns Hopkins University; Aaron Fisher, Johns Hopkins University; Jon Steingrimsson, Johns Hopkins University; Joshua A Betz, Johns Hopkins University
2:25 PM

Expanding the Survey of Doctorate Recipients
Wan-Ying Chang, NSF/NCSES; Daniel Foley, NSF/NCSES; Karen Grigorian, NORC; Michael Yang, NORC; Lance Selfa, NORC
2:25 PM

Bayesian Interval Based Dose Finding Designs and a Web-Based Statistical Tool
Yuan Ji, NorthShore University HealthSystem/University of Chicago; Sue-Jane Wang, FDA; Shengjie Yang, NorthShore University HealthSystem
2:45 PM

More Information Is Better! Where Do We Get it and How Do We Use It?
Stephanie Michelle Coffey, U.S. Census Bureau; JPSM University of Maryland
4:05 PM

Investigation on Combining Phase II Proof-Of-Concept Trial with Dose Finding Trial
Yutao Liu, Columbia University; Qiqi Deng, Boehringer Ingelheim Pharmaceuticals, Inc.; Ken Cheung, Deptment of Biostatistics, Columbia University
4:05 PM

Modeling Nonresponse Bias Likelihood and Response Propensity: The Design and Implementation of Statistical Models to Identify Cases for Interventions During Data Collection
Daniel Pratt, RTI International; Jeffrey Rosen, RTI International; Michael Duprey, RTI International; Jamie Wescott, RTI International
4:20 PM

Adaptive Design and Statistical Consideration in Clinical Trials
Steven Sun; Grace Liu, Johnson & Johnson; Tianmeng Lyu, Univ. Minnesota Biostatistics Dept.
4:25 PM

Basket Trial Considerations in Phase Ib/IIa Oncology Studies of Targeted Therapy
Yihua Zhao, Boehringer Ingelheim Pharmaceuticals, Inc.
4:45 PM

Evaluation of Adaptive Sample Size Re-estimation (SSR) Designs:start small then ask for more?
Chaofeng Liu
5:05 PM

Monday, 07/31/2017
A Bayesian Adaptive Design in Cancer Phase I Trials Using Dose Combinations with Ordinal Toxicity Grades
Sungjin Kim, Cedars-Sinai Medical Center; Marcio Diniz, Cedars Sinai Medical Center; Mourad Tighiouart, Cedars-Sinai Medical Center


Sample Size Re-Estimation and Other Midcourse Adjustments with Sequential Parallel Comparison Design
Rachel Silverman, University of North Carolina; Anastasia Ivanova, UNC at Chapel Hill


A Site-Adjusted Approach to the Covariate-Adjusted Response-Adaptive Allocation Design in Multi-Center Trials
Brian Di Pace, Virginia Commonwealth Univ; Roy T Sabo, Virginia Commonwealth University
10:50 AM

Estimators and Confidence Intervals for Adaptive Two-Stage Designs for Population Enrichment
Vladimir Dragalin, Janssen R&D; Ionut Bebu, The George Washington University
10:55 AM

An Embedded Experiment for Targeted Nonresponse Follow-Up in Establishment Surveys
Stephen Kaputa, U.S. Census Bureau; Katherine Thompson, U.S. Census Bureau; Jennifer Beck, National Science Foundation
11:50 AM

Adaptive Design by Benchmarked Sequential Sampling and Benchmarked Multiple Imputation
Shin-Jung Lee, University of Michigan
12:05 PM

A Simple and Flexible Graphical Approach for Adaptive Group-Sequential Clinical Trials
Frank Bretz, Novartis AG; Toshifumi Sugitani, Astellas; Willi Maurer, Novartis
2:05 PM

Confirmatory Group Sequential Adaptive Designs for Time-To-Event Endpoints Using a Short-Term Endpoint for Treatment Arm or Population Selection
Gernot Wassmer, Medical University of Vienna, Austria; Martin Posch, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University o; Franz Koenig, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University o; Silke Joergens, ICON Clinical Research Inc, Cologne Germany
3:05 PM

Tuesday, 08/01/2017
Tests and Classifications in Adaptive Designs with Applications
Qiusheng Chen, Florida State University; Xufeng Niu, Florida State University
8:35 AM

A Practical Bayesian Adaptive Design with Application to Cardiovascular Outcomes Trials
Matthew Psioda, UNC Chapel Hill; Joseph G Ibrahim, UNC; Mat Soukup, Center for Drug Evaluation and Research, Office of Translational Sciences, FDA
9:05 AM

Earning Regulatory Approval for a Phase II/III Design: a Case Study from Start to Finish
Adam Hamm, Cytel, Inc.
9:20 AM

Adaptive Designs in Phase II Basket Clinical Trials
Kristen Cunanan; Alexia Iasonos, Memorial Sloan Kettering Sloan Cancer Center; Ronglai Shen, Memorial Sloan Kettering Cancer Center; Colin Begg, Memorial Sloan Kettering Cancer Center; Mithat Gonen, Memorial Sloan Kettering Cancer Center
9:35 AM

New Adaptive Designs of Clinical Trial for Precision Medicine
Feifang Hu, George Washington University
10:35 AM

Statistical Considerations for an Adaptive Design for a Serious Rare Disease
Gary R Cutter, UAB School of Public Heatlh Department of Biostatistics
11:25 AM

Multi-Arm Multi-Stage Group Sequential Design in Clinical Trial
Pranab Ghosh, Cytel Inc, Boston University; Cyrus Mehta, Cytel Inc
11:50 AM

An Evaluation of Increasing Sample Size Based on Conditional Power
Michael Gaffney, Pfizer Inc.
2:05 PM

Efficiency Considerations for Group Sequential Designs with Adaptive Unblinded Sample Size Re-Assessment
Sam Hsiao, Cytel, Inc; Lingyun Liu, Cytel, Inc; Cyrus Mehta, Cytel Inc
2:25 PM

Adapting the 5-Zone Adaptive Design
Yi Liu, Takeda; Mingxiu Hu, Takeda Pharmaceutical
3:05 PM

Implementation of Promising Zone Methodology in a Ph 3 Trial in AML (VALOR)
Jennifer Smith, Sunesis
3:25 PM

Wednesday, 08/02/2017
Statistical Considerations for Rare Disease Clinical Development
Yang Song, Vertex Pharmaceuticals


BOP2: Bayesian Optimal Designs for Phase II Clinical Trials with Simple and Complex Endpoints
Heng Zhou, MD Anderson Cancer Center; Ying Yuan, M.D. Anderson Cancer Center
8:35 AM

Edit Reduction: Identifying Possible Stopping Points and Moving Toward Adaptive Design Techniques
Lisa Kaili Diamond, US Census Bureau; Justin Nguyen, U.S. Census Bureau; Brian Arthur Dumbacher, U.S. Census Bureau
11:20 AM

Model-based Design for the Early Development of Cancer Immunotherapy Combinations
Nolan Wages, University of Virgina
11:35 AM

An Optimal Covariate-Adaptive Design to Balance Tiers of Covariates
Fan Wang; Feifang Hu, George Washington University
11:50 AM

Practical Considerations on Simulations for Adaptive Dose Escalation and Dose Ranging Trials
Inna Perevozskaya, Glaxo SmithKline; Alun Bedding, Roche UK; Vladimir Dragalin, Janssen R&D; Parvin Fardipour, ICON
2:25 PM

Simulation Considerations for Multistage Adaptive Designs and Designs with Sample Size Re-Estimation: Type 1 Error Control and Beyond
Greg Cicconetti, Abbvie; Sergei Leonov, ICON Clinical Research; Yili L Pritchett, MedImmune; Michael Smith, Astellas; Alan Hartford, AbbVie
2:45 PM

Thursday, 08/03/2017
Motivation and Design of the DIA Adaptive Design Scientific Working Group (DIA ADSWG) Survey for the Perception and Use of Adaptive Designs in Pharmaceutical Clinical Development
Alan Hartford, AbbVie
10:35 AM

Literature Review Providing a Summary of Adaptive Design Usage in Pharmaceutical Clinical Development
Xiaotian Chen
11:15 AM

Perception and Use of Adaptive Designs in Industry and Academia - Findings of a Review of Registries
Lingyun Liu, Cytel, Inc
11:35 AM

The Adaptive "learn-As-You-Go" Design for Multi-Stage Intervention Studies
Daniel Nevo, Harvard T.H. Chan School of Public Health; Judith Lok, Harvard T H Chan School of Public Health; Donna Spiegelman, Harvard T.H. Chan School of Public Health
11:35 AM

Comparison of the DIA Adaptive Design Scientific Working Group Surveys Conducted from 2000 Through 2015, with an emphasis on perceived and persistent barriers to adoption
Alun Bedding, Roche UK
11:55 AM

 
 
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